As high performance computing (HPC) converges with artificial intelligence (AI) and quantum computing, supercomputing customers are required to find the system performance, flexibility and reliability to fuel the research that will create world-changing discoveries.
With its latest innovations, HPE delivers powerful, efficient system architecture to support customers’ multi-faceted workloads and rise to the great responsibilities of this converged era.
In November 2025, HPE launched a new supercomputing architecture with industry-leading compute density1 designed to meet AI demands at-scale with direct liquid-cooling to power second-generation exascale performance and customers’ groundbreaking research in medicine, climate and materials science.
Today, HPE is introducing a new approach to supercomputing programming software to simplify customers’ experiences, and for the first time, the software is available to HPE ProLiant Compute servers to offer consistency across HPE systems. HPE is also introducing multi-tenant capabilities within networking and storage for high-performance computing, creating one of the industry’s broadest portfolios of end-to-end supercomputing solutions for national labs’ sovereign AI research. Lastly, new financial services improve customers’ control, security and oversight in retiring their advanced computing infrastructure.
A new way of programming
Software developers have a critical pain point: tightly integrated stacks that are difficult to update with the fast pace of change in HPC and AI. That complexity comes with a risk of destabilization associated with assembling, validating and maintaining multi-vendor programming toolchains.
New HPE Supercomputing Programming Software brings a simple approach to multi-vendor environments and the integration process, helping accelerate deployment cycles, and minimizing the risk of system instability. The software also extends to HPE ProLiant Compute servers, including HPE ProLiant DL and XD servers that are optimized for various AI training, tuning and inferencing workloads to enable a consistent, simplified experience across platforms for large enterprises.
Key elements of HPE Supercomputing Programming Software include:
Pre-validating programming environments – The software integrates vendor, open source and HPE tools, validates them into a single programming environment to simplify setup and deployment for customers.
Delivering updates as containerized environments – The software delivers all programming tool updates as a pre-validated, containerized environment, allowing customers to adopt new tools at their own pace by providing ready-to-use, consistent and isolated setups. This approach enhances the stack’s stability, and it provides developers with safer, more efficient updates. Further, the software can implement the same environment across systems without any rebuilds, so developer teams don’t have to start over every time infrastructure changes.
Taking on first-call for multi-vendor support – HPE takes on first-call support, so customers don’t carry the burden of serving as a vendor coordinator. Leveraging HPE’s Cray supercomputing platform expertise, HPE performs technical triage and drives issues to resolution across all vendors.
End-to-end multi-tenancy capabilities for sovereign AI research
Multi-tenant capabilities are crucial for laboratories to run independent management and secure separation of users or critical workloads. HPE is adding multi-tenant networking and storage functionalities to create a full stack of multi-tenant solutions for sovereign AI research, resulting in stronger data security for sensitive workloads on large-scale AI systems.
Networking for high performance computing – To enable sovereign AI research on the network level, HPE launches a new version of HPE Slingshot 400 software with multi-tenancy functionalities based on media access control learning that enforce secure separation of users and restrict unauthorized routing from other groups like open-source and third party. The new multi-tenant capabilities can be applied to HPE Slingshot 400 switches that have already been deployed by customers.
Storage for high performance computing – To set up and manage multi-tenancy in HPE’s supercomputing file system, HPE developed fine-grained multi-tenancy setup and management through new graphical user interface (GUI) and application programming interface (API), simplifying operations for the HPE Cray Supercomputing Storage Systems E2000 in multi-tenant environments. The new GUI makes set up and management of multi-tenancy more intuitive, while the API allows for efficiency improvements through automation in large-scale multi-tenancy environments.
HPE Cray Supercomputing platform answers customers’ multi-tenant needs for secure separation of users with a unified AI and HPC architecture, supported by innovative direct liquid-cooling for improved energy efficiency.
Customers often have stringent requirements when retiring their supercomputing and AI systems, especially because these machines conduct pioneering science and research in accordance with environmental, legal and regional sovereign standards. HPE’s system retirement process is a critical part of excellent customer service.
Built on decades of expertise, HPE Technology Renewal Centers handle the most complex and demanding end-of-use asset management securely and efficiently. In 2025, 85% of servers that went through the renewal centers were upcycled and returned to active use, and 1.7 exabyte of data was securely sanitized.
To enhance support for air-cooled HPC and AI systems, HPE Financial Services is introducing new retirement capabilities. These services improve customers’ control, security and oversight in the process. To ensure a comprehensive and trustworthy system retirement, HPE teams work with customers to address security and configuration resets, proprietary testing, workload validation, advanced diagnostics, scale-out validation and trade compliance assurance. This process enables restoring systems back to factory settings to help safeguard data, ensure regulatory compliance, and responsibly manage hardware assets.
With these new innovations of simplified software, multi-tenant systems, and secure end-of-use capabilities, HPE is enabling advanced solutions for customers’ groundbreaking research and science, from deployment to retirement.
